What is a common association with gender dysphoria?

Gender dysphoria is often associated with an increased prevalence of several mental health conditions, particularly mood disorders. Major depressive disorder is a common comorbidity in individuals with gender dysphoria. The distress stemming from the incongruence between one’s experienced or expressed gender and the sex assigned at birth can lead to feelings of hopelessness, sadness, and worthlessness, which are characteristics of depression. The societal stigma, discrimination, and difficulties faced during transitions can exacerbate these feelings, contributing to a higher incidence of depressive episodes among these individuals.

While anxiety disorders may also be co-occurring, the direct link to major depressive disorder is particularly strong and noteworthy due to the significant psychological impact that gender dysphoria can have on an individual's mental health. This connection underscores the importance of mental health support for individuals experiencing gender dysphoria.